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The week in Science
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The Bundibugyo outbreak widened while limited treatment options, uneven testing, mistrust, and access problems complicated containment. Vaccine development and international care efforts expanded, but rising case counts and response gaps kept control uncertain.
Evidence that epigenetic marks can produce non-Mendelian inheritance in mice was followed by the first precise base edits in human embryos. Together, the findings extend the scientific path from explaining inherited change to making it more directly controllable.
Research identified two routes by which ecosystems could lose carbon-storage capacity: nitrogen pollution can sharply alter forest soil respiration, while rising seas can destabilize mangrove soils and release stored carbon.
A clinical trial found that daraxonrasib nearly doubled survival and cut the risk of death by about 60% in advanced pancreatic cancer. The result marks a major advance against KRAS-driven tumors, which have resisted targeted treatment.
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